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What is SGPT (Serum Glutamic Pyruvic Transaminase)?

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Serum glutamic pyruvic transaminase is the full form of SGPT. It is an enzyme which is normally present in liver and heart cells. When the heart or liver are damaged in any person then SGPT is released into blood. Some times the level of SGPT is elevated as soon as the liver gets damaged due to viral hepatitis or heart gets damaged due to heart attack. Sometimes the levels of SGPT are also raised due to some medications. This condition is also known as alanine aminotransferase (ALT).

There are many causes of increased levels of SGPT. The normal range of SGPT is 20-40 u/l. Some of the important causes -

1. Inflammation in the liver due to hepatitis A, B, C, Infectious mononeuceosis, acute viral fever, ALCOHOL, disorder in pancreas).

2. Due to accidents some injury to the muscles.

3. Acute kidney failure.

4. Certain drugs like cocaine.

5. Drugs for reducing cholesterol etc.

Treatment for high SGPT level depends upon the cause. If proper care is taken for the exact causative factor then the enzymes will gradually become normal like in case of viral hepatitis A, B, C. It is necessary to discontinue alcohol and certain hepato toxic drugs.



It is a known fact that the elevated levels of SGPT is the indication of the existence of different other medical problems like viral hepatitis, liver damage, bile duct problems, congestive heart failure, infectious mononucleosis or myopathy. SGPT is also known by the name of ALT (Alanine Transaminase). Usually it is found in serum and in different tissues of the body, but mainly it is associated with the liver.

The fluctuations in the levels of SGPT are normal over the course of the day. Sometimes the level of the SGPT also increases due to strenuous physical exercise. With the proper measurement of enzymes, the possible underlying causes can be easily found out. For example if the levels of SGPT is increased due to the damage in the liver cell which can easily be distinguished from the problems of biliary duct by the measurement of alkaline phosphate.

The problem of increased levels of SGPT can be controlled easily by diet restrictions as well as proper rest. Plenty of fruits are advisable for lowering the levels of SGPT. The person suffering from high levels of SGPT must avoid non-vegetarian diet and must avoid pickles. The suffering person must drink plenty of fresh and boiled water. The sufferer must drink vegetables juices. They must eat simple light liquid diet. They must eat fat-free and oil free food.





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